Which is the best pain relief gel in India?
In our day, work never ends. Overexploitation of our muscles and joints can cause aches and pains, which may require immediate treatment. Stiff knees, a painful back, and other aching joints can make regular chores seem difficult. Gels and creams offer a deep-penetrating composition that relieves muscular and joint pain and stiffness. These products contain anti-inflammatory ingredients that inhibit pain. Many of us seek out pain-relieving products as an alternative since they ease, soothe, and lessen the discomfort.
Let’s take a look at the top six pain relief gels in India.
![]() |
Volini pain relief cream |
Moov Gel
If you're looking for a topical pain reliever that is safe, effective and has a long-lasting effect, then Moov gel is the product for you. Moov Gel is a doctor-recommended gel that helps people with urgent local pain relief. They present the latest pain relief technology, and Moov gel offers quick and effective repose from various sources of pain, such as headaches, toothaches, muscle aches, and arthritis. If you're looking for an effective and long-lasting solution to your chronic pain problems, then Moov gel is what you need! Moov gel is free from pain, and the FDA has approved this topical pain reliever as safe and effective. Moov gel is a soothing and effective alternative to oral pain medications. Use it today, and let us help you live a pain-free life!
![]() |
Dr. Ortho Ointment |
Himani Fast Relief
Sanofi India markets Combiflam Icy Hot Gel, a topical analgesic, to healthcare customers. Icy Hot Gel is an OTC medicine available in gel and spray forms. It provides immediate and long-lasting relief for muscle strains and injuries. Combiflam Icy Hot Gel is a fast-acting pain relief gel that combines the benefits of cooling and heating therapy. Infused with menthol and methyl salicylate, it provides instant cooling to numb pain, followed by a warming effect that relaxes muscles and improves blood circulation. This dual-action formula effectively relieves muscle aches, joint pain, sprains, strains, and sports injuries. The non-greasy, quick-absorbing gel ensures targeted relief without any sticky residue, making it convenient for daily use. Ideal for individuals seeking immediate and long-lasting comfort, Combiflam Icy Hot Gel is a trusted choice for pain management.
![]() |
Omnigel |
Volini from Sun Pharma stands out as the most trusted and preferred pain relief gel. In India, choosing the best pain relief gel goes beyond just popularity—we consider customer satisfaction, credibility, effectiveness, availability, repurchase trends, and brand reputation.
What is the mode of action of Pain relief gels?
Pain relief gels deliver active ingredients through the skin to the affected muscles or joints, reducing pain, inflammation, and stiffness.
Their mode of action depends on the ingredients used. Here’s how they typically work:
1. Anti-inflammatory action (NSAIDs-based gels)
- Example: Diclofenac, Ibuprofen, Ketoprofen
- These gels contain non-steroidal anti-inflammatory drugs (NSAIDs) that inhibit cyclooxygenase (COX-1 and COX-2) enzymes.
- This action blocks the production of prostaglandins, which are responsible for pain, inflammation, and swelling.
2. Counter-Irritant Effect (Cooling & Warming Sensation)
- Example: Menthol, Methyl Salicylate, Camphor
- These ingredients create a cooling or warming effect that distracts pain receptors in the skin.
- This sensation reduces pain perception by blocking pain signals to the brain (Gate Control Theory of Pain).
3. Local Anesthetic Action (Numbing the Area)
- Example: Lidocaine, Benzocaine
- These ingredients temporarily numb the nerve endings in the applied area, blocking pain signals and providing relief.
4. Vasodilation & Blood Flow Enhancement
- Example: Capsaicin
- Capsaicin depletes Substance P (a pain neurotransmitter) and increases blood circulation, reducing pain over time.
- It is particularly effective in chronic pain conditions like arthritis and neuropathy.
5. Muscle Relaxation & Reduced Stiffness
- Some gels contain essential oils or natural extracts that relax muscles and reduce stiffness.
- Increased blood flow in the area promotes healing and faster recovery.
Application & Absorption
- The gel penetrates the epidermis and dermis layers of the skin.
- Active ingredients reach underlying tissues, muscles, and joints to provide relief.
- They avoid systemic side effects (like oral NSAIDs affecting the stomach) because they act locally.
Conclusion
Pain relief gels work through multiple mechanisms—anti-inflammatory effects, nerve signal blocking, counter-irritation, vasodilation, and muscle relaxation. Their effectiveness depends on the type of pain, active ingredients, and proper application to the affected area.